FB2026_02 , released June 18, 2026
Allele: Dmel\Ank2RNAi.UAS
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General Information
Symbol
Dmel\Ank2RNAi.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0194845
Feature type
allele
Associated gene
Dmel\Ank2
Associated Insertion(s)
Carried in Construct
P{UAS-Ank2.RNAi}
Key Links
Transgenic product class
RNAi_reagent
(Yamamoto, 2006)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Yamamoto, 2006)
Mutagen
in vitro construct
(Yamamoto, 2006)
Progenitor genotype
Carried in construct
P{UAS-Ank2.RNAi}
Cytology
Description

UAS regulatory sequences drive expression of an inverted repeat of Ank2 cDNA, corresponding to amino acid residues 25-190.

(Yamamoto, 2006)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Ank2
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In

      dorsal multidendritic neuron ddaE & axon, with Scer\GAL4pk-IG1-1

      (Yamamoto et al., 2006)
      Detailed Description
      Statement
      Reference

      Expression of Ank2dsRNA.Scer\UAS under the control of Scer\GAL4IG1-1 (resulting in the production of Ank2 dsRNA) in embryos results in the formation of ectopic branches on the ddaE neuron.

      (Yamamoto et al., 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Transcription from the P{UAS-Ank2.RNAi} construct should produce Ank2 dsRNA, resulting in dsRNA interference (RNAi) of the Ank2 gene.

      (Yamamoto, 2006)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      Ank2RNAi.UAS
      Ank2dsRNA.Scer\UAS
      Ank2dsRNA.UAS
      ankRNAi
      (Yamamoto et al., 2006)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)