FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\GLaz4.2kb.GFP
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General Information
Symbol
Dmel\GLaz4.2kb.GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0196334
Feature type
allele
Associated gene
Dmel\GLaz
Associated Insertion(s)
Carried in Construct
P{GLaz-GFP}
Key Links
Transgenic product class
genomic_DNA
(Sanchez, 2006)
wild_type
(Sanchez, 2006)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Sanchez, 2006)
wild_type
(Sanchez, 2006)
Mutagen
in vitro construct
(Sanchez, 2006, Sanchez et al., 2006)
Progenitor genotype
Carried in construct
P{GLaz-GFP}
Cytology
Description

4.2kb of GLaz sequence, including 1.8kb of GLaz 5' flanking sequence and 2.4kb of GLaz genomic coding sequence, is fused at the C-terminal end with a GFP tag.

(Sanchez, 2006)
Allele components
Component
Use(s)
Regulatory region(s)
GLaz
Encoded product / tool
GLaz
Tagged with
GFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  spinocerebellar ataxia 1
      modeled by Hsap\ATXN182Q.UAS
      (Del Caño-Espinel et al., 2015)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      GLaz4.2kb.GFP rescues GLazΔ2

      (Sanchez et al., 2006)
      Comments

      When GLaz4.2kb.T:Avic\GFP is placed in a GLazΔ2 background, the survival upon paraquat treatment returns to control levels. Starvation sensitivity is also recovered, with a 66.2% increase in median survival time when comparing GLaz4.2kb.T:Avic\GFP GLazΔ2 to GLazΔ2 flies. The size and morphology of the fat body is also restored.

      (Sanchez et al., 2006)
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      GLaz4.2kb.GFP
      GLaz4.2kb.T:Avic\GFP
      Name Synonyms
      Secondary FlyBase IDs
        References (5)