FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Hsap\PQBP1UAS.cYa
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General Information
Symbol
Hsap\PQBP1UAS.cYa
Species
H. sapiens
Name
Saccharomyces cerevisiae UAS construct a of Yoshimura
FlyBase ID
FBal0196598
Feature type
allele
Associated gene
Hsap\PQBP1
Associated Insertion(s)
Carried in Construct
P{UAS-hPQBP1.Y}
Key Links
Transgenic product class
cDNA
(Yoshimura et al., 2006)
wild_type
(Yoshimura et al., 2006)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Yoshimura et al., 2006)
wild_type
(Yoshimura et al., 2006)
Mutagen
in vitro construct
(Yoshimura et al., 2006)
Progenitor genotype
Carried in construct
P{UAS-hPQBP1.Y}
Cytology
Description

UASt regulatory sequences drive expression of a 0.8 kb EcoRI-XhoI fragment containing Hsap\PQBP1 cDNA.

(Yoshimura et al., 2006)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Hsap\PQBP1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 1 )
      Disease
      Evidence
      References
      model of  intellectual disability
      CEA
      (Yoshimura et al., 2006)
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The morphology, body weight, and locomotion of flies expressing Hsap\PQBP1Scer\UAS.cYa under the control of Scer\GAL4elav.PLu is not significantly different from those of control flies.

      Flies expressing Hsap\PQBP1Scer\UAS.cYa under the control of Scer\GAL4elav.PLu exhibit a decline in long-term memory in comparison to control flies. However, the learning ability of these flies is not inferior to that of control flies.

      Male flies expressing Hsap\PQBP1Scer\UAS.cYa under the control of Scer\GAL4elav.PLu exhibit abnormal courtship behaviour approximately 80% of the time, compared to never in control flies.

      (Yoshimura et al., 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Expressed in plasmid "pUAST-hPQBP1" in Drosophila Schneider cells.

      (Yoshimura et al., 2006)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Hsap\PQBP1Scer\UAS.cYa
      Hsap\PQBP1UAS.cYa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Yoshimura
      Secondary FlyBase IDs
        References (1)