FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\pcsRNAi.UAS
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General Information
Symbol
Dmel\pcsRNAi.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0197553
Feature type
allele
Associated gene
Dmel\pcs
Associated Insertion(s)
Carried in Construct
P{UAS-pcs.RNAi}
Key Links
Transgenic product class
RNAi_reagent
(Beckett and Baylies, 2006)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Beckett and Baylies, 2006)
Mutagen
in vitro construct
(Beckett and Baylies, 2006)
Progenitor genotype
Carried in construct
P{UAS-pcs.RNAi}
Cytology
Description

UASt regulatory elements drive expression of a pcs hairpin double-stranded RNA, corresponding to full-length pcs cDNA with a 500bp Avic\GFP linker to separate the pcs strands.

(Beckett and Baylies, 2006)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
pcs
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of pcsdsRNA.Scer\UAS under the control of both Scer\GAL4twi.PB and Scer\GAL4Mef2.PR results in embryonic muscle loss and defects in muscle morphogenesis. The specification of founder competent myoblasts is not affected.

      (Beckett and Baylies, 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Transcription from the P{UAS-pcs.dsRNA} construct should produce pcs dsRNA, resulting in dsRNA interference (RNAi) of the pcs gene.

      (Beckett and Baylies, 2006)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      pcsRNAi.UAS
      pcsdsRNA.Scer\UAS
      pcsdsRNA.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (2)