FB2026_02 , released June 18, 2026
Allele: Dmel\CblRing.S.αTub84B
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General Information
Symbol
Dmel\CblRing.S.αTub84B
Species
D. melanogaster
Name
FlyBase ID
FBal0197823
Feature type
allele
Associated gene
Dmel\Cbl
Associated Insertion(s)
Carried in Construct
P{tub-Cbl.Ring}
Key Links
Transgenic product class
missense_variant
(Jekely et al., 2005)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Jekely et al., 2005)
Mutagen
in vitro construct
(Jekely et al., 2005)
Progenitor genotype
Carried in construct
P{tub-Cbl.Ring}
Cytology
Description

The αTub84B promoter drives expression of the Cbl S isoform, mutated to carry a C369A amino acid replacement.

(Jekely et al., 2005)
Allele components
Component
Use(s)
Regulatory region(s)
αTub84B
Encoded product / tool
Cbl
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      CblRing.S.αTub84B fails to rescue CblF165

      (Jekely et al., 2005)
      Comments

      Lethality due to CblF165/CblF165 is not rescued by CblC369A.SαTub84B.PJ and neither is the border cell migration defect seen in CblF165 homozygous somatic clones.

      (Jekely et al., 2005)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      CblRing.S.αTub84B
      Name Synonyms
      Secondary FlyBase IDs
        References (1)