FB2026_03 , released September 17, 2026
Allele: Dmel\Or43aUAS.EGFP
Open Close
General Information
Symbol
Dmel\Or43aUAS.EGFP
Species
D. melanogaster
Name
FlyBase ID
FBal0210981
Feature type
allele
Associated gene
Dmel\Or43a
Associated Insertion(s)
Carried in Construct
P{UAS-Or43a.EGFP}
Key Links
Transgenic product class
wild_type
(Benton et al., 2006)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Benton et al., 2006)
Mutagen
in vitro construct
(Benton et al., 2006)
Progenitor genotype
Carried in construct
P{UAS-Or43a.EGFP}
Cytology
Description

UAS regulatory sequences drive expression of full-length Or43a, which is tagged at the N-terminus with EGFP.

(Benton et al., 2006)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Or43a
Tagged with
EGFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Coexpression of Or83bScer\UAS.cBa and Or43aScer\UAS.T:Avic\GFP-EGFP, under the control of Scer\GAL4Gr21a.9.323, reconstitutes a functional odorant receptor as measured in neurons that also express the calcium-sensitive reporter Ggal\MLCK::Rat\CamG-CaMP.Scer\UAS.T:Avic\GFP-cpEGFP. Without the expression of Or83bScer\UAS.cBa and Or43aScer\UAS.T:Avic\GFP-EGFP the Ggal\MLCK::Rat\CamG-CaMP.Scer\UAS.T:Avic\GFP-cpEGFP-expressing neurons can respond to CO2 but not cyclohexanol. Once Or83bScer\UAS.cBa and Or43aScer\UAS.T:Avic\GFP-EGFP are expressed, neurons can respond to cyclohexanol, cyclohexanone, hexanol, benzaldehyde, isoamyl acetate, and geranyl acetate; odors specific to the Or43a receptor.

      (Benton et al., 2006)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Or43aScer\UAS.T:Avic\GFP-EGFP
      Or43aUAS.EGFP
      Name Synonyms
      Secondary FlyBase IDs
        References (1)