FlyBase Allele Report: Dmel\tim[s]

General Information

Symbol

Dmel\tim^s

Species

D. melanogaster

Name

FlyBase ID

FBal0211084

Feature type

allele

Associated gene

Dmel\tim

Associated Insertion(s)

Carried in Construct

Also Known As

s-tim

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

natural population

Nature of the Allele

Allele class

Mutagen

natural population

(Peschel et al., 2006)

Progenitor genotype

Cytology

Description

Contains a single base-pair G deletion at position 294, preventing translation from an alternative translation start codon and resulting in the production of only the "short" tim isoform.

(Peschel et al., 2006)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

deletion

2L:3,504,475..3,504,475 [-]

Comment:

Contains a single base-pair G deletion at position 294, preventing translation from an alternative translation start codon and resulting in the production of only the "short" tim isoform.

(Peschel et al., 2006)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

tim^s flies kept in constant light conditions show locomotor arrhythmicity, as do wild-type flies.

tim^s flies show a larger phase response to light pulses than tim^ls flies.

(Sandrelli et al., 2007)

tim^s females from northern populations show a higher incidence of reproductive arrest than those from southern populations.

(Tauber et al., 2007)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

tim^s, jet^c show behavioral arrhythmicity in constant light conditions, like wild-type flies.

(Peschel et al., 2006)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

s-tim

(Roessingh et al., 2019, Grima et al., 2012, Chen et al., 2011, Dolezelova et al., 2007, Sandrelli et al., 2007, Tauber et al., 2007, Tauber et al., 2007, Peschel et al., 2006, Van Gelder, 2006)

tim^s

Name Synonyms

Secondary FlyBase IDs

References (9)

Report Sections

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