FB2026_02 , released June 18, 2026
Allele: Dmel\exdnes.nls2.178-300.UAS.GFP,Tag:MYC
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General Information
Symbol
Dmel\exdnes.nls2.178-300.UAS.GFP,Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0212129
Feature type
allele
Associated gene
Dmel\exd
Associated Insertion(s)
Carried in Construct
P{UAS-myc-GFP-exd.178-300.nes.nls2}
Key Links
Transgenic product class
inframe_deletion
(Stevens and Mann, 2007)
missense_variant
(Stevens and Mann, 2007)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Stevens and Mann, 2007)
missense_variant
(Stevens and Mann, 2007)
Mutagen
in vitro construct
(Stevens and Mann, 2007)
Progenitor genotype
Carried in construct
P{UAS-myc-GFP-exd.178-300.nes.nls2}
Cytology
Description

UAS regulatory sequences drive expression of exd amino acid residues 178-300, with mutations in both the nuclear export signal (NES) (amino acid replacements I209A, F213A, I216A and M218A) and exd nuclear localization signal 2 (NLS2) (residues 291 and 292 have been mutated to Ala residues). The protein is tagged at the N-terminal end with Tag:MYC and GFP.

(Stevens and Mann, 2007)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
exd
Tagged with
GFP
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      exdnes.nls2.178-300.Scer\UAS.T:Avic\GFP,T:Hsap\MYC
      exdnes.nls2.178-300.UAS.GFP,Tag:MYC
      Name Synonyms
      Secondary FlyBase IDs
        References (1)