FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\TwdlDΔ173-175.Tag:FLAG
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General Information
Symbol
Dmel\TwdlDΔ173-175.Tag:FLAG
Species
D. melanogaster
Name
FlyBase ID
FBal0212142
Feature type
allele
Associated gene
Dmel\TwdlD
Associated Insertion(s)
Carried in Construct
P{TwdlD.Δ173-175}
Key Links
Transgenic product class
inframe_deletion
(Guan, 2006)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Guan, 2006)
Mutagen
in vitro construct
(Guan, 2006)
Progenitor genotype
Carried in construct
P{TwdlD.Δ173-175}
Cytology
Description

Wild-type TwdlD coding sequence, with a small 3-amino acid deletion (position 173-175, amino acids KYR) is placed downstream of a presumptive TwdlD promoter and tagged at the C-terminus with Tag:FLAG.

(Guan, 2006)
Allele components
Component
Use(s)
Regulatory region(s)
TwdlD
Encoded product / tool
TwdlD
Tagged with
Tag:FLAG
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Pupae expressing TwdlDΔ173-175.T:Zzzz\FLAG exhibit a readily observable squat phenotype.

      Two copies of TwdlDΔ173-175.T:Zzzz\FLAG have a greater effect on body shape than a single copy. In particular, pupae carrying two copies of the mutant transgene have a mean axial ratio of 2.1-2.2.

      (Guan et al., 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      TwdlDΔ173-175.T:Zzzz\FLAG
      TwdlDΔ173-175.Tag:FLAG
      Name Synonyms
      Secondary FlyBase IDs
        References (2)