FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Hmgcr26.31
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General Information
Symbol
Dmel\Hmgcr26.31
Species
D. melanogaster
Name
FlyBase ID
FBal0212248
Feature type
allele
Associated gene
Dmel\Hmgcr
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
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        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        From anaysis of cuticles - Hmgcr26.31/Hmgcr26.31 embryos often have fused segments - most commonly fusion of segments 7 and 8. In some cases these embryos have more severe patterning defects (segment fusions and deletions; extra denticles in some segments) characteristic of mutations in segment polarity genes.

        (Deshpande and Schedl, 2005)

        Normal separation of primordial germ cells into lateral clusters on each side of the embryo is observed in Hmgcr26.31 mutants.

        (Sano et al., 2005)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        Hmgcr26.31
        (Barton et al., 2024)
        hmgcr26.31
        (Deshpande and Schedl, 2005, Deshpande and Schedl, 2005, Sano et al., 2005)
        Name Synonyms
        Secondary FlyBase IDs
          References (4)