FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\osk13TTgAY
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General Information
Symbol
Dmel\osk13TTgAY
Species
D. melanogaster
Name
FlyBase ID
FBal0212699
Feature type
allele
Associated gene
Dmel\osk
Associated Insertion(s)
Carried in Construct
P{osk.13TTgAY}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Munro et al., 2006)
Progenitor genotype
Carried in construct
P{osk.13TTgAY}
Cytology
Description

All 13 copies of the IBE (Imp-binding element) which are present in the osk 3' UTR are mutated from TTTAC/T to TTTgC/T in an otherwise wild-type genomic osk fragment.

(Munro et al., 2006)
Allele components
Component
Use(s)
Encoded product / tool
osk
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments

      osk13TTgAY rescues the stage 6 oocyte arrest phenotype of oskA87/Df(3R)p-XT103 females. However, embryos derived from oskA87/Df(3R)p-XT103;osk13TTgAY mothers display a fully penetrant osk mutant maternal-effect phenotype in which the abdomen fails to form.

      (Munro et al., 2006)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      osk13TTgAY.mat
      osk13TTgAY
      (Munro et al., 2006)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)