FB2026_02 , released June 18, 2026
Allele: Dmel\egr66
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General Information
Symbol
Dmel\egr66
Species
D. melanogaster
Name
FlyBase ID
FBal0212742
Feature type
allele
Associated gene
Dmel\egr
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Wang et al., 2006)
Mutagen
P-element activity
(Wang et al., 2006)
Progenitor genotype
P{SUPor-P}KG02299
(Wang et al., 2006)
Cytology
Description

Imprecise excision of the P{SUPor-P} element resulting in a deletion of 7kb that uncovers the entire egr transcription unit, without extending into neighbouring genes.

(Wang et al., 2006)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The survival rate of egr66 mutant flies following challenge with either Staphylococcus aureus or Enterococcus faecalis is similar to wild type.

      (Geuking et al., 2009)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      egr66
      (Ruan et al., 2013, Geuking et al., 2009, Wang et al., 2006)
      eiger66
      (Geuking et al., 2009)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)