FB2026_03 , released September 17, 2026
Allele: Dimm\oskM103,106L.imm3'mel
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General Information
Symbol
Dimm\oskM103,106L.imm3'mel
Species
D. immigrans
Name
FlyBase ID
FBal0212747
Feature type
allele
Associated gene
Dimm\osk
Associated Insertion(s)
Carried in Construct
P{Dimm\oskM103,106L.imm3'mel}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Jones and Macdonald, 2007)
Progenitor genotype
Carried in construct
P{Dimm\oskM103,106L.imm3'mel}
Cytology
Description

Genomic fragment that encompasses Dimm\osk; includes 5kb upstream of the start codon and extends to the end of the Dimm\osk coding sequence. A 1.6kb HindIII-Asp718 fragment that encodes the osk 3'UTR and downstream sequence is present downstream of the Dimm\osk coding sequence. Both of the methionine residues near the predicted translation start site of the short Dimm\osk isoform have been mutated (amino acid replacements M103L and M106L).

(Jones and Macdonald, 2007)
Allele components
Component
Use(s)
Encoded product / tool
Dimm\osk
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Dimm\oskM103,106L.imm3'mel in wild-type D. melanogaster embryos does not cause a partial transformation of pole cell nuclear bodies towards the morphology observed in D. immigrans embryos. This is in contrast to transgenes that express the short isoform of Dimm\osk, which can mediate this transformation.

      (Jones and Macdonald, 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Dimm\oskM103,106L.imm3'mel
      Name Synonyms
      Secondary FlyBase IDs
        References (1)