FB2026_02 , released June 18, 2026
Allele: Dmel\α-Spec::β-Specα13.Ubi-p63E.Tag:MYC
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General Information
Symbol
Dmel\α-Spec::β-Specα13.Ubi-p63E.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0212751
Feature type
allele
Associated gene
α-Spec::β-Spec
Associated Insertion(s)
Carried in Construct
P{Ubi-p63E-α-Spec::β-Spec.α13}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Das et al., 2006)
Progenitor genotype
Carried in construct
P{Ubi-p63E-α-Spec::β-Spec.α13}
Cytology
Description

An Ubi-p63E promoter drives expression of β-Spec, in which the 15th repeat (the putative ankyrin-binding segment 16) has been replaced with segment 13 of α-Spec. The construct is tagged with Tag:MYC.

(Das et al., 2006)
Allele components
Component
Use(s)
Regulatory region(s)
Ubi-p63E
Encoded product / tool
α-Spec::β-Spec
Tagged with
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments

      Expression of α-Spec::β-Specα13.Ubi-p63E.T:Hsap\MYC rescues the axon guidance defects of β-Specem6/Y embryos.

      (Garbe et al., 2007)

      Expression of α-Spec::β-Specα13.Ubi-p63E.T:Hsap\MYC rescues around 17% of β-Specem21 male flies. Many of the rescued progeny are fertile but some exhibit minor wing defects and many die during eclosion.

      (Das et al., 2006)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      α-Spec::β-Specα13.Ubi-p63E.T:Hsap\MYC
      α-Spec::β-Specα13.Ubi-p63E.Tag:MYC
      βspecα13
      (Das et al., 2006)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)