FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Hsap\YAP1ΔC61.UAS
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General Information
Symbol
Hsap\YAP1ΔC61.UAS
Species
H. sapiens
Name
FlyBase ID
FBal0212820
Feature type
allele
Associated gene
Hsap\YAP1
Associated Insertion(s)
Carried in Construct
P{UAS-Hsap\YAP1.ΔC61}
Key Links
Transgenic product class
frameshift_truncation
(Hoshino et al., 2006)
Mutagen
Nature of the Allele
Transgenic product class
frameshift_truncation
(Hoshino et al., 2006)
Mutagen
in vitro construct
(Hoshino et al., 2006)
Progenitor genotype
Carried in construct
P{UAS-Hsap\YAP1.ΔC61}
Cytology
Description

UASt regulatory sequences drive expression of Hsap\YAP1 coding sequences in which a 61 nucleotide insert causes a reading frame shift, resulting in truncation of the C-terminal transcriptional activation domain.

(Hoshino et al., 2006)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Hsap\YAP1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  Huntington's disease
      modeled by Hsap\HTTGMR.Q120
      (Hoshino et al., 2006)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Expression of Hsap\YAP1ΔC61.Scer\UAS in the developing and adult eye, under the control of Scer\GAL4GMR.long suppresses disruption of photoreceptor neurons and ommatidial structure in Hsap\HDGMR.Q120/Scer\GAL4GMR.long flies.

      (Hoshino et al., 2006)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Hsap\YAP1ΔC61.Scer\UAS
      Hsap\YAP1ΔC61.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (3)