FB2026_03 , released September 17, 2026
Allele: Dmel\M(3)96Cunspecified
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General Information
Symbol
Dmel\M(3)96Cunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0215270
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    Wild-type clones grow more rapidly in a M(3)96Cunspecified/+ background than in a +/+ background.

    When +/+ clones are induced in a M(3)96Cunspecified/+ background and cell death is analysed, apoptotic cells are largely restricted to boundaries between wild-type and M(3)96Cunspecified/+ cell populations and the apoptotic cells are almost always M(3)96Cunspecified/+. Apoptotic material is sometimes present within neighbouring, wild-type epithelial cells, indicating that some of the apoptotic cells are cleared by engulfment into neighbouring cells.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    Additional Comments
    Genetic Interactions
    Statement
    Reference

    When homozygous WASpEY06238 clones (which are M(3)96C+) are induced in a M(3)96Cunspecified/+ background, cell competition appears to be reduced, as the M(3)96Cunspecified/+ cells contribute to more of the territory and show reduced cell death compared to experiments where they are competing against +/+ cells.

    When homozygous PSREY07193 clones (which are M(3)96C+) are induced in a M(3)96Cunspecified/+ background, cell competition appears to be reduced, as the M(3)96Cunspecified/+ cells contribute to more of the territory and show reduced cell death compared to experiments where they are competing against +/+ cells.

    When homozygous mbcEY01437 clones (which are M(3)96C+) are induced in a M(3)96Cunspecified/+ background, cell competition appears to be reduced, as the M(3)96Cunspecified/+ cells contribute to more of the territory and show reduced cell death compared to experiments where they are competing against +/+ cells.

    When homozygous PSRnull clones (which are M(3)96C+) are induced in a M(3)96Cunspecified/+ background, cell competition appears to be reduced, as the M(3)96Cunspecified/+ cells contribute to more of the territory compared to experiments where they are competing against +/+ cells.

    Xenogenetic Interactions
    Statement
    Reference

    Expression of BacA\p35Scer\UAS.cHa under the control of Scer\GAL4en-e16E increases the contribution of M(3)96Cunspecified/+ cells and decreases the contribution of +/+ cells in the posterior compartment of wing discs containing +/+ clones in a M(3)96Cunspecified/+ background.

    The more rapid growth of wild-type clones in a M(3)96Cunspecified/+ background (compared to a +/+ background) is eliminated if they are also expressing BacA\p35Scer\UAS.cHa under the control of Scer\GAL4en-e16E.

    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (1)
    Reported As
    Symbol Synonym
    M(3)96Cunspecified
    Name Synonyms
    Secondary FlyBase IDs
      References (3)