FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\stwl95
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General Information
Symbol
Dmel\stwl95
Species
D. melanogaster
Name
FlyBase ID
FBal0216706
Feature type
allele
Associated gene
Dmel\stwl
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Ovaries from wild-type females retain germ cells for more than 3 weeks, but stwlz1/stwl95 females show a dramatic and rapid loss of germ cells, with approximately 50% of ovarioles lacking germ cells by 10 days post-eclosion.

        Wild-type germline stem cell (GSC) clones are maintained for over 2 weeks in the germarium, whereas most homozygous stwl95 GSC clones are rapidly depleted.

        (Maines et al., 2007)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        Approximately 80% of stwl95 bamΔ86 double mutant female germaria contain germ cells interconnected by branched fusomes, indicating that cystoblasts have formed and initiated cyst differentiation. On average, 30% of germ cells in these ovaries are in clusters penetrated by branched fusomes.

        (Maines et al., 2007)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        stwl95
        (Maines et al., 2007)
        Name Synonyms
        Secondary FlyBase IDs
          References (1)