FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Ggal\SerpinI1UAS.cOa
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General Information
Symbol
Ggal\SerpinI1UAS.cOa
Species
G. gallus
Name
Saccharomyces cerevisiae UAS construct a of Osterwalder
FlyBase ID
FBal0216767
Feature type
allele
Associated gene
Ggal\SerpinI1
Associated Insertion(s)
Carried in Construct
P{UAS-Neus.O}
Transgenic product class
cDNA
(Osterwalder et al., 2004)
wild_type
(Osterwalder et al., 2004)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Osterwalder et al., 2004)
wild_type
(Osterwalder et al., 2004)
Mutagen
in vitro construct
(Osterwalder et al., 2004)
Progenitor genotype
Carried in construct
P{UAS-Neus.O}
Cytology
Description

UASt regulatory sequences drive expression of a 1.6kb Ggal\SerpinI1 coding sequence derived from the sc13a1 cDNA sequence.

(Osterwalder et al., 2004)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Ggal\SerpinI1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Lethality and molting defects are observed when Ggal\SerpinI1Scer\UAS is expressed using Scer\GAL4how-24B to drive expression in muscles and other mesodermally derived tissues, nerves, and trachea, as well as a subset of cells in the CNS (with the larvae arresting development at the L1 to L2 ecdysis).

      Larvae overexpressing Ggal\SerpinI1Scer\UAS under the control of Scer\GAL4how-24B or Scer\GAL4dimm-929 are able to proceed to the sclerotised double mouthhooks and double ventral plates stage normally but then remain trapped there for up to 24 hours (compared to the whole period lasting for about 1 hour in wild-type).

      (Osterwalder et al., 2004)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      Ggal\SerpinI1Scer\UAS.cOa
      Ggal\SerpinI1Scer\UAS
      Ggal\SerpinI1UAS.cOa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Osterwalder
      Secondary FlyBase IDs
        References (2)