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General Information
Symbol
Dmel\mmyunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0217374
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    In stage 16 mmyunspecified embryos, the trachea is aberrantly permeable to a fluorescently labelled 10kDa dextran in some stretches of the dorsal trunk, but not in others. At the end of embryogenesis, the dorsal trunk of mmyunspecified mutants has a highly disorganized structure and displays constrictions and dilations. The luminal envelope is formed but there are no taenidial folds. Microvillae are still present, while such structures are undetectable by this stage in wild-type trachea. The tracheal lumen shows a detachment between the cell membranes and the envelope. mmyunspecified embryos have no recognizable cuticular structures and no denticle belts or hairs. No chitin or N-acetylglucosamine is detectable in the epidermis of mmyunspecified embryos. The procuticle, that is composed of stacks of highly organized chitin laminae, is missing and underlying epithelial cells appear detached in many places. However, the envelope and the epicuticle, which are chitin-free, maintain remnants of their structure.

    mmyunspecified mutant embryos have poorly differentiated mouthparts and denticles.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    Additional Comments
    Genetic Interactions
    Statement
    Reference

    The tracheal defects of sinuunspecified mutant embryos are more severe in double mutant combination with mmyunspecified.

    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (3)
    Reported As
    Symbol Synonym
    caounspecified
    cystunspecified
    mmyunspecified
    Name Synonyms
    Secondary FlyBase IDs
    • FBal0095489
    • FBal0086407
    • FBal0155417
    References (7)