FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Ecol\lacZSCE
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General Information
Symbol
Ecol\lacZSCE
Species
E. coli
Name
FlyBase ID
FBal0219118
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
SCE-lacZ
Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

A 1kb fragment of genomic DNA surrounding two tin-binding sites in the svp genomic region is cloned to a minimal promoter-lacZ reporter gene.

Allele components
Component
Use(s)
Regulatory region(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
distribution deduced from reporter
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Information
Statement
Reference

At stage 11, the EcollacZSCE enhancer is active in seven sets of cells in the most dorsal part of the mesoderm. EcollacZSCE is also active in additional cells slightly ventral to this, precursors of dorsal somatic muscles. There is also enhancer activity in cells closely apposed to the ventral ectoderm, which are likely to be a subset of the neuroblasts previously shown to express svp. During stage 12, enhancer activity intensifies in the dorsal mesoderm, and is still overlapping with tin. At stage 14, EcollacZSCE activity is strong in both the svp-positive cells of the dorsal vessel and in the dorsal somatic muscles. At stage 16, EcollacZSCE can be seen in all seven clusters of svp-positive cells, and small amounts of residual signal can be detected in the svp-positive pericardial cells.

 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Ecol\lacZSCE
Name Synonyms
Secondary FlyBase IDs
    References (3)