UAS regulatory sequences drive expression of an inverted repeat.
Expression of SNF4AγJF02060 in the fat body under the control of Scer\GAL4DcG results in significant hyperglycaemia.
Expression of SNF4AγJF02060 in muscle under the control of Scer\GAL4Mef2.PU results in significant hyperglycaemia.
Down-regulation of SNF4Aγ pan-neuronally, through expression of SNF4AγJF02060 under the control of Scer\GAL4elav-C155 does not result in a detectable degenerative phenotype in 14 day old flies. However, these flies reveal a performance index of only 48 in a fast phototaxis assay.
Down-regulation of SNF4Aγ, through expression of SNF4AγJF02060 under the control of Scer\GAL4Appl.G1a and Scer\GAL4elav-C155 results in a degenerative phenotype in 14 day old flies.