FlyBase Allele Report: Dmel\Smr[JF02413]

General Information

Symbol

Dmel\Smr^JF02413

Species

D. melanogaster

Name

FlyBase ID

FBal0220758

Feature type

allele

Associated gene

Dmel\Smr

Associated Insertion(s)

Carried in Construct

P{TRiP.JF02413}

Also Known As

JF02413

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Perkins et al., 2009.3.31)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Perkins et al., 2009.3.31)

Mutagen

in vitro construct

(Perkins et al., 2009.3.31)

Progenitor genotype

Carried in construct

P{TRiP.JF02413}

Cytology

Description

UAS regulatory sequences drive expression of an inverted repeat.

(Perkins et al., 2009.3.31)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-JF02413

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal size | adult stage, with Scer\GAL4^ey.PH

(Dietz et al., 2015)

abnormal size | adult stage, with Scer\GAL4^GMR.PF

(Dietz et al., 2015)

lethal, with Scer\GAL4^Act5C.PI

(Dietz et al., 2015)

lethal, with Scer\GAL4^en.PU

(Dietz et al., 2015)

melanotic mass phenotype, with Scer\GAL4^{SPARC-MI00329-GAL4}

(Zang et al., 2015)

partially lethal - majority die, with Scer\GAL4^ey.PH

(Dietz et al., 2015)

visible | adult stage, with Scer\GAL4^ey.PH

(Dietz et al., 2015)

visible | adult stage, with Scer\GAL4^GMR.PF

(Dietz et al., 2015)

visible | adult stage, with Scer\GAL4^nub.PK

(Dietz et al., 2015)

Phenotype Manifest In

eye, with Scer\GAL4^ey.PH

(Dietz et al., 2015)

eye, with Scer\GAL4^GMR.PF

(Dietz et al., 2015)

fat body, with Scer\GAL4^{SPARC-MI00329-GAL4}

(Zang et al., 2015)

melanotic mass, with Scer\GAL4^{SPARC-MI00329-GAL4}

(Zang et al., 2015)

wing blade, with Scer\GAL4^nub.PK

(Dietz et al., 2015)

Detailed Description

Statement

Reference

Expression of Smr^JF02413 results in reduced rough eye phenotype (with Scer\GAL4^GMR.PF), unfurled wings (with Scer\GAL4^nub.PK - same phenotype at 18[o]C) and is lethal (with Scer\GAL4^Act5C.PI), pupal lethal with Scer\GAL4^ey.PH (escapers have small eyes, rough eye phenotype is observed at 18[o]C) as well as with Scer\GAL4^en.PU (same result at 18[o]C).

(Dietz et al., 2015)

Expression of Smr^JF02413 in the fat body under the control of Scer\GAL4^DcG results in significant hyperglycaemia.

Expression of Smr^JF02413 in the fat body under the control of Scer\GAL4^DcG results in significant lower trehalose levels than controls.

(Ugrankar et al., 2015)

Expression of Smr^JF02413 under the control of Scer\GAL4^{SPARC-MI00329-GAL4} results in melanisation of the fat body.

(Zang et al., 2015)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

27068

y¹ v¹; P{TRiP.JF02413}attP2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Smr^JF02413

Name Synonyms

Secondary FlyBase IDs

References (7)

Report Sections

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