FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Fkbp395-HA-2440
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General Information
Symbol
Dmel\Fkbp395-HA-2440
Species
D. melanogaster
Name
FlyBase ID
FBal0226515
Feature type
allele
Associated gene
Dmel\Fkbp39
Associated Insertion(s)
P{RS5}Fkbp395-HA-2440
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{RS5}Fkbp395-HA-2440
    Cytology
    Description

    Insertion in the 5' UTR, 49bp upstream of the translation start codon.

    (Juhász et al., 2007)
    Allele components
    Component
    Use(s)
    Also carries
    FRT
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Mutant flies show no obvious developmental abnormality or delay under normal conditions.

        FK506-bp15-HA-2440/Df(3R)Exel6194 larvae show a significantly higher level of autophagy in response to a short 80 minute starvation compared to controls.

        (Juhász et al., 2007)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (3)
        Reported As
        Symbol Synonym
        FK506-bp15-HA-2440
        FKBP395-HA-2440
        (Juhász et al., 2007)
        Fkbp395-HA-2440
        Name Synonyms
        Secondary FlyBase IDs
          References (2)