FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Nep1KK101227
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General Information
Symbol
Dmel\Nep1KK101227
Species
D. melanogaster
Name
FlyBase ID
FBal0231136
Feature type
allele
Associated gene
Dmel\Nep1
Associated Insertion(s)
Carried in Construct
P{KK101227}
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Keleman et al., 2009.8.5)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Keleman et al., 2009.8.5)
Mutagen
in vitro construct
(Keleman et al., 2009.8.5)
Progenitor genotype
Carried in construct
P{KK101227}
Cytology
Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
dsRNA-KK101227
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Nep1KK101227 under the control of either Scer\GAL4c739 or Scer\GAL4VT064246 (using tub-Gal80[ts] to limit the expression to adulthood) do not impair middle-term memory tested in an aversive olfactory memory assay 2hr post-training.

      (Turrel et al., 2017)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Adult flies expressing both Nep1KK101227 and ApplAβ.Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4c739 (combined with tub-Gal80[ts] to limit expression to adulthood) do not show any defects in middle-term memory (MTM) tested in an aversive olfactory memory assay 2hr post-training, whereas with the Scer\GAL4VT064246 driver, the MTM is significantly reduced.

      (Turrel et al., 2017)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Nep1KK101227
      Nep1RNAi2
      (Turrel et al., 2020)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)