FB2025_05 , released December 11, 2025
Allele: Dmel\mldrKK108043
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General Information
Symbol
Dmel\mldrKK108043
Species
D. melanogaster
Name
FlyBase ID
FBal0235330
Feature type
allele
Associated gene
Dmel\mldr
Associated Insertion(s)
Carried in Construct
P{KK108043}
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Keleman et al., 2009.8.5)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Keleman et al., 2009.8.5)
Mutagen
in vitro construct
(Keleman et al., 2009.8.5)
Progenitor genotype
Carried in construct
P{KK108043}
Cytology
Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
dsRNA-KK108043
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 1 )
      Disease
      Evidence
      References
      model of  combined oxidative phosphorylation deficiency 54
      CEC
      (Saoji et al., 2022)
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of mldrKK108043 under the control of either Scer\GAL4αTub84B.PL or Scer\GAL4Act5C.PI leads to partial lethality: only a small proportion of flies manage to eclose although majority of larvae pupariate.

      Expression of mldrKK108043 under the control of Scer\GAL4ple.PF results in age-progressive decrease in the ability of adult flies to climb.

      (Sen et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Enhancer of
      NOT Suppressor of
      Statement
      Reference

      mldrKK108043, Scer\GAL4GMR.PU is a non-suppressor of visible | adult stage phenotype of Hsap\MAPTR406W.UAS, Scer\GAL4GMR.PU

      (Shafik et al., 2022)
      Phenotype Manifest In
      NOT Enhancer of
      Statement
      Reference

      mldrKK108043, Scer\GAL4GMR.PU is a non-enhancer of eye phenotype of Hsap\MAPTR406W.UAS, Scer\GAL4GMR.PU

      (Shafik et al., 2022)
      NOT Suppressor of
      Statement
      Reference

      mldrKK108043, Scer\GAL4GMR.PU is a non-suppressor of eye phenotype of Hsap\MAPTR406W.UAS, Scer\GAL4GMR.PU

      (Shafik et al., 2022)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      CG15896KK108043
      mldrKK108043
      Name Synonyms
      Secondary FlyBase IDs
        References (5)