FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\glob1KK109839
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General Information
Symbol
Dmel\glob1KK109839
Species
D. melanogaster
Name
FlyBase ID
FBal0236508
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

UASt regulatory sequences drive expression of an inverted repeat.

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of glob1KK109839 under the control of Scer\GAL4da.G32 in long term hypoxic conditions results in significant reduction in survival rate and median survival time.

Expression of glob1KK109839 under the control of Scer\GAL4da.G32 in short term severe hypoxic conditions results in female flies (but not male) having significantly decreased survival rate.

Expression of glob1KK109839 under the control of Scer\GAL4da.G32 results in significantly reduced recovery time after anoxic stupor in female flies only, but does not affect reaction time to anoxia in either sex.

Expression of glob1KK109839 under the control of Scer\GAL4da.G32 in normoxic conditions results in no significant change in lifespan or length of developmental stages, and in hyperoxic conditions does not change survival rate relative to controls.

Expression of glob1KK109839 under the control of Scer\GAL4da.G32, when exposed to paraquat-induced oxidative stress during 3rd instar larval stage, significantly increases survival to adulthood. When exposed to paraquat-induced oxidative stress during adult stage, expression of glob1KK109839 under the control of Scer\GAL4da.G32 results in significantly higher survival rate of females (but not males) within the first 55hrs of exposure.

No difference in the amount of lipid peroxidation or oxidative DNA damage observed in adult flies expressing glob1KK109839 under the control of Scer\GAL4da.G32 when exposed to oxidative stress via paraquat or hyperoxia.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
glob1KK109839
Name Synonyms
Secondary FlyBase IDs
    References (2)