FlyBase Allele Report: Dmel\CG9775[KK110941]

General Information

Symbol

Dmel\CG9775^KK110941

Species

D. melanogaster

Name

FlyBase ID

FBal0237123

Feature type

allele

Associated gene

Dmel\CG9775

Associated Insertion(s)

Carried in Construct

P{KK110941}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK110941}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK110941

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

exacerbates amyotrophic lateral sclerosis

modeled by Zzzz\GGGGCC^58.UAS.EGFP

(Freibaum et al., 2015)

exacerbates frontotemporal dementia

modeled by Zzzz\GGGGCC^58.UAS.EGFP

(Freibaum et al., 2015)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal circadian rhythm | adult stage, with Scer\GAL4^ey-OK107

(Machado Almeida et al., 2021)

increased sleep | adult stage | male, with Scer\GAL4^ey-OK107

(Machado Almeida et al., 2021)

Phenotype Manifest In

Detailed Description

Statement

Reference

Expression of CG9775^KK110941 under the control of Scer\GAL4^GMR.PU does not result in any apparent eye defects, as compared to controls.

(Freibaum et al., 2015)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

CG9775^KK110941, Scer\GAL4^GMR.PU is an enhancer of visible phenotype of Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP

(Freibaum et al., 2015)

Phenotype Manifest In

Enhancer of

Statement

Reference

CG9775^KK110941, Scer\GAL4^GMR.PU is an enhancer of eye phenotype of Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP

(Freibaum et al., 2015)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Co-expression of CG9775^KK110941 enhances the rough eye phenotype seen in flies expressing Zzzz\GGGGCC^{58.Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^GMR.PU.

(Freibaum et al., 2015)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v108437

P{KK110941}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

CG9775^KK110941

CHTOP^108437/KK

(Freibaum et al., 2015)

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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