UASt regulatory sequences drive expression of an inverted repeat.
Expression of rdgAKK113317 under the control of Scer\GAL4Act5C.Switch.PR and treated with RU486 from day 1 of adulthood, results in increased lifespan of adults grown under either dietary restriction (0.5% yeast) or an ad libitum diet (5% yeast) media, as compared to controls.
Expression of rdgAKK113317 under the control of Scer\GAL4sal.BO (in combination with a Dicer-2 transgene to enhance RNAi efficiency) does not result in larval lethality at the L2/L3 transition.