M band & indirect flight muscle, with Scer\GAL41151
myofibril & indirect flight muscle, with Scer\GAL41151
Z disc & indirect flight muscle, with Scer\GAL41151
Expression of mib2dsRNA.Scer\UAS under the control of Scer\GAL41151 results in defects in the indirect flight muscles (IFMs) of newly emerged adults; the M bands are poorly defined, and the Z bands are less dense than normal and occasionally have a zigzagging shape. 2-3 day old flies are flightless and unable to jump and their thoraces have empty cavities, due to a loss of muscle mass. The remaining IFMs lack myofibrils, although both thick and thin filaments are present, and only possess remnants of electron-dense material, which resemble Z bands.