FB2026_03 , released September 17, 2026
Allele: Dmel\lgs::pygoΔHD1.Y748A.L789A.Tag:HA
Open Close
General Information
Symbol
Dmel\lgs::pygoΔHD1.Y748A.L789A.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0239136
Feature type
allele
Associated gene
lgs::pygo
Associated Insertion(s)
Carried in Construct
P{pygo-pygo::lgs.ΔHD1.Y748A.L789A}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Kessler et al., 2009)
Progenitor genotype
lgs::pygowt.Tag:HA
(Kessler et al., 2009)
Carried in construct
P{pygo-pygo::lgs.ΔHD1.Y748A.L789A}
Cytology
Description

Deletion of sequences encoding lgs amino acid residues 318-345 (the HD1 domain), plus mutation of two pygo amino acid residues (the changes are Y748A and L789A).

(Kessler et al., 2009)
Allele components
Component
Use(s)
Regulatory region(s)
pygo
Encoded product / tool
lgs::pygo
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments

      lgs::pygoΔHD1.Y748A.L789A.T:Ivir\HA1 is able to rescue the phenotype of lgs20F/lgs20F and pygo130/pygo130 single mutants, and of lgs20F/lgs20F pygo130/pygo130 double mutants.

      (Kessler et al., 2009)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      lgs::pygoΔHD1.Y748A.L789A.T:Ivir\HA1
      lgs::pygoΔHD1.Y748A.L789A.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (1)