FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Desat1NIG.5887R
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General Information
Symbol
Dmel\Desat1NIG.5887R
Species
D. melanogaster
Name
FlyBase ID
FBal0239160
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

UASt regulatory sequences drive expression of a Desat1 RNAi construct.

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Flies expressing desat1NIG.5887R under the control of Scer\GAL41407 show normal locomotor activity.

Flies expressing desat1NIG.5887R under the control of Scer\GAL41407 show a dramatic change in their hydrocarbon profile compared to controls, with an almost complete disappearance of unsaturated hydrocarbons (decrease of 96% in males and of 78% in females). The level of saturated linear hydrocarbons is multiplied 4 times in both sexes compared to control flies. In females, total dienes and pheromones are decreased by 90% amd monoenes by 40%.

The percentage of wild-type males performing courtship towards control females or females expressing desat1NIG.5887R under the control of Scer\GAL41407 is similar, but the courtship latency is 4 times higher when the female is expressing desat1NIG.5887R under the control of Scer\GAL41407. Males attempting and succeeding in copulation are fewer (down 45% and 70% respectively) when the female is expressing desat1NIG.5887R under the control of Scer\GAL41407 compared to control females, and the times required for these behaviours (up 112% and 28% respectively) is increased.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Desat1NIG.5887R
desat1NIG.5887R
Name Synonyms
Secondary FlyBase IDs
    References (2)