FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Tpl94DEGFP
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General Information
Symbol
Dmel\Tpl94DEGFP
Species
D. melanogaster
Name
FlyBase ID
FBal0239754
Feature type
allele
Associated gene
Dmel\Tpl94D
Associated Insertion(s)
Carried in Construct
P{Tpl94D-eGFP.R}
Also Known As
Tpl94D-eGFP
Key Links
Transgenic product class
wild_type
(Rathke et al., 2007)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Rathke et al., 2007)
Mutagen
in vitro construct
(Rathke et al., 2007)
Progenitor genotype
Carried in construct
P{Tpl94D-eGFP.R}
Cytology
Description

The open reading frame of Tpl94D, together with 446bp upstream of the ATG start codon is fused with EGFP.

(Rathke et al., 2007)
Allele components
Component
Use(s)
Regulatory region(s)
Tpl94D
Tpl94D_tpl-94D-eGFP
Encoded product / tool
Tpl94D
Tagged with
EGFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      immunolocalization
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      adult stage | male
      mid-late elongation-stage spermatid
      (Rathke et al., 2007)
      Additional Information
      Statement
      Reference

      Tpl94D-eGFP transiently expressed in spermatids at the time when the switch from a histone-based to a protamine-based chromatin configuration occurs. It is first detected in early canoe stage spermatids shortly before the histones disappear. It is most strongly expressed at late canoe stage when protamines are visible and the histones have disappeared. It is no longer detected when the chromatin is completely condensed.

      (Rathke et al., 2007)
       
      Marker for
      Reflects expression of
      Tpl94D
      (Rathke et al., 2007)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Tpl94DEGFP
      Tpl94DT:Avic\GFP-EGFP
      Name Synonyms
      Secondary FlyBase IDs
        References (5)