FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\NFATΔa1
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General Information
Symbol
Dmel\NFATΔa1
Species
D. melanogaster
Name
FlyBase ID
FBal0239768
Feature type
allele
Associated gene
Dmel\NFAT
Associated Insertion(s)
Carried in Construct
Also Known As
NFATΔa
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Keyser et al., 2007)
Progenitor genotype
P{EP}NFATEP1353
(Keyser et al., 2007)
Cytology
Description

Imprecise excision of the progenitor insertion, causing a deletion that results in a lack of detectable transcription from the NFAT a promoter.

(Keyser et al., 2007)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  Alzheimer's disease 1
      modeled by Hsap\APP695.UAS.Tag:MYC
      (Shao et al., 2022)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      NFATΔa1 mutants exhibit minimal differences in neuromuscular junction size.

      (Freeman et al., 2011)

      Mutants have no obvious morphological defects.

      Mutant larvae show normal survival in food containing 0.2M or 0.4M NaCl.

      (Keyser et al., 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Bloomington
      33593
      w1118 NFATΔa1
      Availability

      Stated to be lost.

      (Keyser et al., 2007)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      NFATΔa1
      NFATΔa
      (Shao et al., 2022, Freeman et al., 2011, Keyser et al., 2007)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)