FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\GαsRNAi.UAS
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General Information
Symbol
Dmel\GαsRNAi.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0240155
Feature type
allele
Associated gene
Dmel\Gαs
Associated Insertion(s)
Carried in Construct
P{UAS-Gαs.RNAi}
Key Links
Transgenic product class
RNAi_reagent
(Ueno et al., 2006)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Ueno et al., 2006)
Mutagen
in vitro construct
(Ueno et al., 2006)
Progenitor genotype
Carried in construct
P{UAS-Gαs.RNAi}
Cytology
Description

UASt sequences govern the expression of Gαs dsRNA (an inverted repeat of nucleotides -42 to 1381).

(Ueno et al., 2006)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Gαs
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of G-sα60AdsRNA.Scer\UAS under the control of Scer\GAL4P0.5.Pdf results in an average circadian period of 25.0 hours, which is significantly longer than the 24.0 or 23.8 hr period of control flies with Scer\GAL4P0.5.Pdf or G-sα60AScer\UAS.cCa alone.

      (Dahdal et al., 2010)

      Expression of G-sα60AdsRNA.Scer\UAS under the control of Scer\GAL4Orco.T:Hsim\VP16 does not reduce the odour response of the ab1A or ab2A olfactory receptor neurons (tested with ethyl acetate) or of the ab3A ORN (tested with methyl butyrate).

      Expression of G-sα60AdsRNA.Scer\UAS under the control of Scer\GAL4Gr21a.9.323 does not reduce the response of the ab1C ORN to CO[[2]].

      (Yao and Carlson, 2010)

      Uptake of 10-80mM trehalose solution is significantly lower in G-sα60AScer\UAS.dsRNA/Scer\GAL41407 flies than in wild-type controls. This effect is not seen with lower concentrations of trehalose.

      Stimulation of long labellar taste bristles with 5-80mM trehalose in G-sα60AScer\UAS.dsRNA/Scer\GAL41407 flies induces significantly more biphasic spikes in associated sensory neurons than seen in wild-type controls.

      (Ueno et al., 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      G-sα60AScer\UAS.dsRNA
      G-sα60AdsRNA.Scer\UAS
      GαsRNAi.UAS
      GαsdsRNA.Scer\UAS
      GαsdsRNA.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (4)