FlyBase Allele Report: Dmel\Caf1-180[HM05129]

General Information

Symbol

Dmel\Caf1-180^HM05129

Species

D. melanogaster

Name

FlyBase ID

FBal0240258

Feature type

allele

Associated gene

Dmel\Caf1-180

Associated Insertion(s)

Carried in Construct

P{TRiP.HM05129}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Perkins et al., 2009)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Perkins et al., 2009)

Mutagen

in vitro construct

(Perkins et al., 2009)

Progenitor genotype

Carried in construct

P{TRiP.HM05129}

Cytology

Description

UAS regulatory sequences drive expression of an inverted repeat.

(Perkins et al., 2009)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HM05129

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal size | adult stage, with Scer\GAL4^ey.PH

(Dietz et al., 2015)

lethal, with Scer\GAL4^Act5C.PI

(Dietz et al., 2015)

lethal, with Scer\GAL4^en.PU

(Dietz et al., 2015)

lethal, with Scer\GAL4^ey.PH

(Dietz et al., 2015)

visible, with Scer\GAL4^en-e16E

(Yu et al., 2013)

visible | adult stage, with Scer\GAL4^en.PU

(Dietz et al., 2015)

visible | adult stage, with Scer\GAL4^ey.PH

(Dietz et al., 2015)

visible | adult stage, with Scer\GAL4^nub.PK

(Dietz et al., 2015)

Phenotype Manifest In

eye, with Scer\GAL4^ey.PH

(Dietz et al., 2015)

posterior crossvein, with Scer\GAL4^nub.PK

(Dietz et al., 2015)

wing, with Scer\GAL4^en.PU

(Dietz et al., 2015)

wing, with Scer\GAL4^en-e16E

(Yu et al., 2013)

wing blade, with Scer\GAL4^nub.PK

(Dietz et al., 2015)

wing vein, with Scer\GAL4^nub.PK

(Dietz et al., 2015)

Detailed Description

Statement

Reference

Expression of Caf1-180^HM05129 is lethal with Scer\GAL4^Act5C.PI, pupal lethal with either Scer\GAL4^ey.PH or Scer\GAL4^en.PU (at 25[o]C, at 18[o]C the flies display small deformed eyes or mild wing defects, respectively). Scer\GAL4^nub.PK-driven expression results in blistered wings with deformed veins and occasional partial loss of posterior crossvein at 25[o]C and in ectopic vein material formation at 18[o]C; no overt adult phenotype is observed with Scer\GAL4^GMR.PF.

(Dietz et al., 2015)

Expression of Caf1-180^HM05129 under the control of Scer\GAL4^en-e16E produces a notched wing phenotype.

(Yu et al., 2013)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

28918

y¹ v¹; P{TRiP.HM05129}attP2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Caf1-180^HM05129

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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