FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\Cad74A38A
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General Information
Symbol
Dmel\Cad74A38A
Species
D. melanogaster
Name
FlyBase ID
FBal0240419
Feature type
allele
Associated gene
Dmel\Cad74A
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Zartman et al., 2008)
Mutagen
P-element activity
(Zartman et al., 2008)
Progenitor genotype
P{EP}GE22619
(Zartman et al., 2008)
Cytology
Description

Imprecise excision of the progenitor insertion, resulting in a deletion of the entire coding region of Cad74A (coordinates of the deletion are nucleotides 209199-221108 of AE003524).

(Zartman et al., 2008)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
3L:17,367,621..17,379,530 [-]
Comment:

Reported as a deletion spanning coordinates 209199в21108 of AE003524.3 (version number determined by the reported Cad74A coordinates as 221107в09329)

(Zartman et al., 2008)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      17% of eggs laid by homozygous females at room temperature lack dorsal appendages, or have dorsal appendages that are significantly deformed or shortened to varying degrees. The eggs are impermeable to Neutral Red, suggesting that the vitelline membrane has been deposited correctly.

      (Zartman et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Cad74A38A
      (Zartman et al., 2008)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)