FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\mir-125UAS.cCa
Open Close
General Information
Symbol
Dmel\mir-125UAS.cCa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Caygill
FlyBase ID
FBal0240494
Feature type
allele
Associated gene
Dmel\mir-125
Associated Insertion(s)
Carried in Construct
P{UAS-mir-125.C}
Also Known As
UAS-mir-125
Key Links
Transgenic product class
wild_type
(Caygill and Johnston, 2008)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Caygill and Johnston, 2008)
Mutagen
in vitro construct
(Caygill and Johnston, 2008)
Progenitor genotype
Carried in construct
P{UAS-mir-125.C}
Cytology
Description

UASt regulatory sequences drive expression of a 188bp fragment containing mir-125.

(Caygill and Johnston, 2008)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
mir-125
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expressing mir-125UAS.cCa under the control of either Scer\GAL4Tub.Switch.PU or Scer\GAL4elav.Switch.PO significantly reduces the adult life span of females treated with RU486 (to switch on transgene expression) compared to untreated controls.

      (Gendron and Pletcher, 2017)

      Expression of mir-125Scer\UAS.cCa under the control of Scer\GAL4vg.PM has no effect on the size of the third instar wing disc or adult wing.

      (Caygill and Johnston, 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      mir-125Scer\UAS.cCa
      mir-125UAS.cCa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Caygill
      Secondary FlyBase IDs
        References (4)