FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\hebePdL
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General Information
Symbol
Dmel\hebePdL
Species
D. melanogaster
Name
FlyBase ID
FBal0240540
Feature type
allele
Associated gene
Dmel\hebe
Associated Insertion(s)
P{PdL}hebePdL
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{PdL}hebePdL
    Cytology
    Description

    P{PdL}hebe is located 6721bp upstream of the hebe translational start site. The 3' end of P{PdL}hebe is oriented towards the open reading frame.

    (Li and Tower, 2009)
    Allele components
    Component
    Use(s)
    Inserted element
    P{PdL}
    Regulatory region(s)
    tetO
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        hebePdL mutants exhibit a 31% increase in median life in males and a 24% increase in mean life span in males. in females, a 2.2% increase in median life span and a 11% increase in mean life span is found.

        hebePdL mutants, where DOX administration is initiated at age 40 days, exhibit increased female fecundity at late ages at one or more DOX concentrations. The late-age administration of drug had no negative effect on female survival.

        (Li and Tower, 2009)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        hebePdL
        Name Synonyms
        Secondary FlyBase IDs
          References (1)