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General Information
Symbol
Dmel\RhoGAP18BΔRC
Species
D. melanogaster
Name
FlyBase ID
FBal0240551
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Imprecise excision of RhoGAP18B1 P-element results in a 625bp deletion in the first RC exon, which is predicted to cause an early termination of the RC ORF.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 1 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

RhoGAP18BΔRC mutants exhibit resistance to ethanol-induced sedation.

RhoGAP18BΔRC mutant flies exhibit significantly reduced loss-of-righting (LOR-refers to the inability of flies to regain upright posture upon mechanical stimulation) compared to control flies.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Fails to complement
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

Based on resistance to enthanol-induced sedation, the following RhoGAP18B alleles can be ranked from strongest to weakest as follows: RhoGAP18B3 > RhoGAP18B1 = RhoGAP18BΔRC.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
RhoGAP18BΔRC
Name Synonyms
Secondary FlyBase IDs
    References (1)