FB2026_03 , released September 17, 2026
Allele: Dmel\msl-3ΔCBD.hs.EGFP
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General Information
Symbol
Dmel\msl-3ΔCBD.hs.EGFP
Species
D. melanogaster
Name
FlyBase ID
FBal0240717
Feature type
allele
Associated gene
Dmel\msl-3
Associated Insertion(s)
Carried in Construct
P{hs-msl-3.ΔCBD.EGFP}
Key Links
Transgenic product class
inframe_deletion
(Buscaino et al., 2006)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Buscaino et al., 2006)
Mutagen
in vitro construct
(Buscaino et al., 2006)
Progenitor genotype
Carried in construct
P{hs-msl-3.ΔCBD.EGFP}
Cytology
Description

A heat shock promoter drives expression of a mutated form of msl-3, which lacks amino acid residues 34-89, and is tagged at the C-terminal end with EGFP.

(Buscaino et al., 2006)
Allele components
Component
Use(s)
Encoded product / tool
msl-3
Tagged with
EGFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments

      Only 8.3% of msl-3083 males carrying msl-3ΔCBD.hs.T:Avic\GFP-EGFP survive to adulthood. The surviving males show a range of abnormalities, including rough eyes, missing bristles and misshapen wings.

      (Buscaino et al., 2006)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      msl-3ΔCBD.hs.EGFP
      msl-3ΔCBD.hs.T:Avic\GFP-EGFP
      Name Synonyms
      Secondary FlyBase IDs
        References (1)