FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\lftNIG.13139R
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General Information
Symbol
Dmel\lftNIG.13139R
Species
D. melanogaster
Name
FlyBase ID
FBal0241156
Feature type
allele
Associated gene
Dmel\lft
Associated Insertion(s)
Carried in Construct
P{NIG.13139R}
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Mao et al., 2009)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Mao et al., 2009)
Mutagen
in vitro construct
(Mao et al., 2009)
Progenitor genotype
Carried in construct
P{NIG.13139R}
Cytology
Description

UASt regulatory sequences drive expression of a hairpin of lft sequences.

(Mao et al., 2009)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
dsRNA-13139R
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of lftNIG.13139R under the control of Scer\GAL4Act results in flies with slightly shorter wings than normal. The reduced length of the wing is most obvious in the middle of the wing, where the distance between the anterior and the posterior crossveins is decreased.

      Expression of lftNIG.13139R under the control of Scer\GAL4en-e16E results in a modest, but statistically significant, increase in the relative size of the posterior compartment of the wing disc (where Scer\GAL4en-e16E is expressed) to 87% of anterior compartment size (in control wing discs, the posterior compartment is 80% of the size of the anterior compartment).

      (Mao et al., 2009)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of lftNIG.13139R enhances the overgrowth of the the posterior compartment of the wing disc that is seen in animals expressing dsGD14350 under the control of Scer\GAL4en-e16E, such that the posterior compartment is 178% of anterior compartment size (in control wing discs, the posterior compartment is 80% of the size of the anterior compartment).

      (Mao et al., 2009)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      lftNIG.13139R
      Name Synonyms
      Secondary FlyBase IDs
        References (3)