FB2026_02 , released June 18, 2026
Allele: Dmel\Cad86CUAS.Tag:HA
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General Information
Symbol
Dmel\Cad86CUAS.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0241663
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

UASt regulatory sequences drive expression of the entire coding sequence of Cad86C, which is tagged at the C-terminal end with three copies of Tag:HA.

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

16% of clones expressing Cad86CScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4Act5C.PP in the eye disc have an unusual shape; they are highly elongated compared to control clones. Cells in these elongated clones are shorter along their apicobasal axis, are apically constricted and are part of an epithelial fold (the fold also contains neighbouring wild-type cells).

17% of clones expressing Cad86CScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4Act5C.PP in the wing disc have a highly elongated shape. The cells in these elongated clones are shorter along their apicobasal axis compared to neighbouring wild-type cells, are apically constricted and are part of an epithelial fold.

The apicobasal length of control cells and of cells expressing Cad86CScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4ap-md544 in the centre of the dorsal compartment of the wing disc is indistinguishable. However, at the dorsal-ventral compartment boundary (Scer\GAL4ap-md544 is expressed in the dorsal compartment), both central control cells and dorsal cells expressing Cad86CScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4ap-md544 sometimes have a highly decreased cell length and are part of an epithelial fold.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Expression of Cad86CScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4Act5C.PP in smo3 tkv4 double homozygous clones in the region of the morphogenetic furrow can result in the formation of an epithelial invagination in some cases. Cells at the centre of this invagination are shorter along their apicobasal axis compared to smo3 tkv4 double homozygous clones or to wild-type cells within the morphogenetic furrow.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Cad86CScer\UAS.T:Ivir\HA1
Cad86CUAS.Tag:HA
Name Synonyms
Secondary FlyBase IDs
    References (1)