FB2026_02 , released June 18, 2026
Allele: Mmus\Mapk8ip1ΔJBD.UAS
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General Information
Symbol
Mmus\Mapk8ip1ΔJBD.UAS
Species
M. musculus
Name
FlyBase ID
FBal0241870
Feature type
allele
Associated gene
Mmus\Mapk8ip1
Associated Insertion(s)
Carried in Construct
P{UAS-Mmus\Mapk8ip1.ΔJBD}
Transgenic product class
inframe_deletion
(Rusu et al., 2007)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Rusu et al., 2007)
Mutagen
in vitro construct
(Rusu et al., 2007)
Progenitor genotype
Carried in construct
P{UAS-Mmus\Mapk8ip1.ΔJBD}
Cytology
Description

UASt regulatory sequences drive expression of Mmus\Mapk8ip1 coding sequences lacking the JBD (JNK-binding domain - residues 68-79).

(Rusu et al., 2007)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Mmus\Mapk8ip1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The axons of larvae expressing Mmus\Mapk8ip1ΔJBD.Scer\UAS (under the control of Scer\GAL4179Y) exhibit vesicle accumulation, indicating a defect in axonal transport.

      The amplitude of basal EJC is unchanged in larvae that express Mmus\Mapk8ip1ΔJBD.Scer\UAS under the control of Scer\GAL4179Y or Scer\GAL4elav-C155 compared to wild-type.

      Post-tetanic potentiation (PTP) is unchanged in larvae that express Mmus\Mapk8ip1ΔJBD.Scer\UAS under the control of Scer\GAL4179Y or Scer\GAL4elav-C155 compared to wild-type.

      (Rusu et al., 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Mmus\Mapk8ip1ΔJBD.Scer\UAS
      Mmus\Mapk8ip1ΔJBD.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (1)