FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Fmr1JF02634
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General Information
Symbol
Dmel\Fmr1JF02634
Species
D. melanogaster
Name
FlyBase ID
FBal0242223
Feature type
allele
Associated gene
Dmel\Fmr1
Associated Insertion(s)
Carried in Construct
P{TRiP.JF02634}
Also Known As
UAS-dfmr1-RNAi
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Perkins et al., 2009)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Perkins et al., 2009)
Mutagen
in vitro construct
(Perkins et al., 2009)
Progenitor genotype
Carried in construct
P{TRiP.JF02634}
Cytology
Description

UAS regulatory sequences drive expression of an inverted repeat.

(Perkins et al., 2009)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
dsRNA-JF02634
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 1 )
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies expressing Fmr1JF02634 under the control of Scer\GAL4hs.PU show significantly decreased performance in a reversal-learning defect as compared to wild type, showing an inability to forget the first aversive odor association after training with a second aversive odor.

      (Dong et al., 2016)

      Expression of Fmr1JF02634 under the control of Scer\GAL4GMR12G04 (either in combination with a Gal80[ts] transgene to restrict expression to the period including pupal day 4 to 1 day post-eclosion, or without a Gal80[ts] for expression throughout development) results in a significant increase in dendritic arbor volume of MVP2 neurons at 1 day post-eclosion, as compared to controls.

      Expression of Fmr1JF02634 under the control of Scer\GAL4GMR65G01 (either in combination with a Gal80[ts] transgene to restrict expression to the period including pupal day 4 to 1 day post-eclosion, or without a Gal80[ts] for expression throughout development) results in a significant increase in dendritic arbor volume of projection neurons at 1 day post-eclosion, as compared to controls.

      (Doll and Broadie, 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Fmr1JF02634
      Name Synonyms
      Secondary FlyBase IDs
        References (9)