FB2026_03 , released September 17, 2026
Allele: Dmel\SuURrs6.UAS
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General Information
Symbol
Dmel\SuURrs6.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0242593
Feature type
allele
Associated gene
Dmel\SuUR
Associated Insertion(s)
Carried in Construct
P{UAS-SuUR.rs6}
Key Links
Transgenic product class
start_lost
(Kolesnikova et al., 2005)
Mutagen
Nature of the Allele
Transgenic product class
start_lost
(Kolesnikova et al., 2005)
Mutagen
ethyl methanesulfonate
(Kolesnikova et al., 2005)
Progenitor genotype
Carried in construct
P{UAS-SuUR.rs6}
Cytology
Description

UAS sequences are fused upstream of SuUR coding sequence into which a M1I amino acid replacement has been introduced. It is possible that translation occurs from Met residues situated at positions 141 and/or 157, as truncated SuUR protein(s) are detected when the construct is expressed.

(Kolesnikova et al., 2005)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
SuUR
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of SuURrs6.Scer\UAS under the control of Scer\GAL4AB1 does not result in the disappearance of weak points in the polytene chromosomes of salivary glands.

      (Kolesnikova et al., 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      SuURrs6.UAS/Scer\GAL4AB1 rescues SuURES

      (Kolesnikova et al., 2005)
      Comments

      Expression of SuURrs6.Scer\UAS under the control of Scer\GAL4AB1 in a SuURES background results in larvae with numerous weak points in intercalary heterochromatin regions (this indicates rescue of the SuURES phenotype of lack of underreplication).

      (Kolesnikova et al., 2005)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      SuURrs6.Scer\UAS
      SuURrs6.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (1)