FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\oskUASp.cSa
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General Information
Symbol
Dmel\oskUASp.cSa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Snee
FlyBase ID
FBal0245138
Feature type
allele
Associated gene
Dmel\osk
Associated Insertion(s)
Carried in Construct
P{UASp-osk.S}
Also Known As
UAS-osk
Key Links
Transgenic product class
wild_type
(Snee et al., 2007)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Snee et al., 2007)
Mutagen
in vitro construct
(Reich et al., 2009, Snee et al., 2007)
Progenitor genotype
Carried in construct
P{UASp-osk.S}
Cytology
Description

UASp regulatory sequences are fused upstream of three segments of osk DNA: a genomic BamHI-EcoRI fragment (starting just upstream of the transcription unit and containing the first eight codons), a cDNA EcoRI-MluI fragment (containing most of the coding region) and a genomic fragment from the MluI site to a synthetic BamHI site introduced just after the stop codon (containing the C-terminal part of the coding region and the final, small intron).

(Snee et al., 2007)
Allele components
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
osk
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of oskScer\UAS.P\T.cRa driven by Scer\GAL4mat.αTub67C.T:Hsim\VP16 results in the disruption of normal anterior embryonic body patterning resulting in a very high frequency of bicaudal embryos.

      (Reich et al., 2009)

      92% of embryos derived from females expressing oskScer\UAS.P\T.cSa under the control of Scer\GAL4mat.αTub67C.T:Hsim\VP16 are bicaudal (having a mirror image duplication of posterior segments).

      (Snee et al., 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The bicaudal phenotype of embryos derived from females expressing oskScer\UAS.P\T.cSa under the control of Scer\GAL4mat.αTub67C.T:Hsim\VP16 is not altered by co-expression of aretScer\UAS.P\T.cSa.

      (Snee et al., 2007)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      oskScer\UAS.P\T.cRa
      oskScer\UAS.P\T.cSa
      oskUASp.cSa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Reich
      Saccharomyces cerevisiae UAS construct a of Snee
      Secondary FlyBase IDs
        References (2)