FB2026_02 , released June 18, 2026
Allele: Dmel\eggG19561
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General Information
Symbol
Dmel\eggG19561
Species
D. melanogaster
Name
FlyBase ID
FBal0245245
Feature type
allele
Associated gene
Dmel\egg
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    This EP line is inserted 60 nucleotides downstream of the egg translation initiation site.

    (Yoon et al., 2008)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        eggG19561 mutants possess ovaries of a markedly reduced size compared with wild-type flies. eggG19561/Df(2R)ED4065 mutants exhibit a slightly more severe phenotype than eggG19561 mutants. Homozygous mutant females are unable to lay eggs, and are therefore sterile. Mutant ovaries carry egg chambers, but these are mostly degenerated in appearance.

        (Yoon et al., 2008)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Other
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        eggG19561; Su(var)3-917 double mutants mostly exhibit a gourd-shaped germaria and defects in the budding off of new egg chambers; as a result, the double mutant has no developing egg chambers in the ovary.

        (Yoon et al., 2008)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        dsetdb1G19561
        (Yoon et al., 2008)
        eggG19561
        Name Synonyms
        Secondary FlyBase IDs
          References (1)