FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\gang-of-fourx
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General Information
Symbol
Dmel\gang-of-fourx
Species
D. melanogaster
Name
FlyBase ID
FBal0246079
Feature type
allele
Associated gene
gang-of-four
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Mosaic animals in which the eyes and head cuticle are composed almost entirely of homozygous tissue (generated using the Minute technique) have consistently larger heads than control flies.

        (Beam and Moberg, 2010)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Enhanced by
        Statement
        Reference

        gang-of-fourx has visible | somatic clone phenotype, enhanceable by Df(3L)H99

        (Beam and Moberg, 2010)
        NOT suppressed by
        Statement
        Reference

        gang-of-fourx, pucE69/puc[+] has lethal | dominant phenotype, non-suppressible by Df(3L)H99/+

        (Beam and Moberg, 2010)

        gang-of-fourx, pucA251.1F3/puc[+] has lethal | dominant phenotype, non-suppressible by Df(3L)H99/+

        (Beam and Moberg, 2010)
        Other
        Statement
        Reference

        gang-of-fourx, pucE69/puc[+] has lethal | dominant phenotype

        (Beam and Moberg, 2010)

        gang-of-fourx, pucA251.1F3/puc[+] has lethal | dominant phenotype

        (Beam and Moberg, 2010)
        Phenotype Manifest In
        Enhanced by
        Statement
        Reference

        gang-of-fourx has adult head | somatic clone phenotype, enhanceable by Df(3L)H99

        (Beam and Moberg, 2010)
        NOT suppressed by
        Statement
        Reference

        gang-of-fourx has ommatidium | somatic clone phenotype, non-suppressible by Df(3L)H99

        (Beam and Moberg, 2010)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        The ommatidial patterning defects seen in homozygous gfrx clones in the pupal eye disc are not suppressed by Df(3L)H99.

        Addition of Df(3L)H99 further increases head size in mosaic animals in which the eyes and head cuticle are composed almost entirely of homozygous gfrx tissue (generated using the Minute technique).

        (Beam and Moberg, 2010)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        gang-of-fourx
        gfrx
        (Beam and Moberg, 2010)
        Name Synonyms
        Secondary FlyBase IDs
          References (1)