FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\SCAP4
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General Information
Symbol
Dmel\SCAP4
Species
D. melanogaster
Name
FlyBase ID
FBal0246160
Feature type
allele
Associated gene
Dmel\SCAP
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Matthews et al., 2010)
Mutagen
FLPase
(Matthews et al., 2010)
Progenitor genotype
PBac{WH}f04534
(Matthews et al., 2010)
PBac{PB}c00785
(Matthews et al., 2010)
Cytology
Description

Recombination between the two progenitor insertions has resulted in the deletion of the sequence between them, which removes the entire SCAP transcription unit.

(Matthews et al., 2010)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
2R:6,026,184..6,036,322 [-]
Comment:

Recombination between the two progenitor insertions has resulted in the deletion of the sequence between them, which removes the entire SCAP transcription unit.

(Matthews et al., 2010)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mutants eclose at approximately 70% of the expected rate, and supplementing the food with fatty acids restores full viability. Homozygous adults appear morphologically indistinguishable from their heterozygous siblings.

      Homozygotes develop more slowly than their heterozygous siblings; beginning approximately 48 hours after egg laying homozygous larvae are noticeably smaller than heterozygotes. Most homozygotes remain as second instar larvae at 89 hours after egg laying (control siblings have mostly reached the third instar by this time). Most homozygotes show delayed pupariation and emerge as adults approximately 2 days after their heterozygous siblings.

      (Matthews et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      SCAP4
      dscap4
      (Matthews et al., 2010)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)