FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\jumuUAS.cHa
Open Close
General Information
Symbol
Dmel\jumuUAS.cHa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Hofmann
FlyBase ID
FBal0246397
Feature type
allele
Associated gene
Dmel\jumu
Associated Insertion(s)
Carried in Construct
P{UAS-jumu.H}
Also Known As
UAS-jumu
Key Links
Transgenic product class
wild_type
(Hofmann et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Hofmann et al., 2010)
Mutagen
in vitro construct
(Hofmann et al., 2010)
Progenitor genotype
Carried in construct
P{UAS-jumu.H}
Cytology
Description

UAS regulatory sequences drive expression of full-length jumu.

(Hofmann et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
jumu
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of jumuScer\UAS.cHa under the control of Scer\GAL4G61 results in the salivary glands of third instar larvae being very small compared to controls and translucent. The size of the fat body is normal in these larvae. Polytene chromosomes are very thin with low levels of polytenisation and the nucleolus is disorganised.

      The salivary glands of third instar larvae expressing jumuScer\UAS.cHa under the control of Scer\GAL4Sgs4.PH are almost normal. However, the nucleolus of the polytene chromosomes is significantly fragmented. In addition, the euchromatin of the polytene chromosomes appears swollen, the chromocenter is nearly always split and the chromosomes are split at the weak points. The nucleus is enlarged and swollen compared to controls in the salivary gland cells.

      (Hofmann et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      jumuScer\UAS.cHa
      jumuUAS.cHa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Hofmann
      Secondary FlyBase IDs
        References (5)